Hair-Exosome
What are exosomes?
Exosomes are extracellular vesicles that are produced by mesenchymal stem cells which are involved in cell communication. Other cells react to the messaging signals from the exosomes and will change their behavior accordingly. Scientists are now able to isolate and deliver these beneficial signalers directly rather than the stem cells themselves.
Exosomes are isolated from donated human amniotic mesenchymal stem cells and purified using proprietary processing. The unique benefit of these exosomes is that they are stem cell-derived and bring a wide array of growth factors. Because they’re so small and nimble, exosomes can remain hidden in the bloodstream, and carry multiple doses of proteins across barriers that cells are not able to cross.
What is exosome therapy for hair loss?
By micro-needling exosomes and growth factors, it has been clinically shown to help regenerate and regrow hair as a treatment for hair loss in both men and women in the earlier stages of hair loss.
Exosomes are stem cells per say. Instead, they are the building blocks of such. They generate within their cells of origin if the multivesicular body fuses with the cell membrane, thereby releasing intraluminal vesicles as exosomes. These small cellular products contain both RNA and, even of greater import, mRNA; the initiator of protein manufacturing.
These protein building blocks' roles are dependent on their cell of origin. Many act as signalers for bodily functions, such as coagulation, as well as cellular growth to facilitate said bodily functions. Such signaling and growth factors, studies currently show, are a result of the exosome's origin. Near all, however, have a number of useful growth factors/signalers:
MIP-1: A recruiter of mononuclear cells
VEGF: A stimulator to encourage blood vessel formation
SCF: An encourager of stem cell and melanocyte growth
FGF: A growth factor that signals cells to encourage biological development
TGFß3: A gene variant that, among other things, converts inflammatory T Cells into anti-inflammatory T-Cells
